Causes of Osteogenesis imperfecta


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Cause of Osteogenesis imperfecta: Also known as "brittle bone disease," this disorder arises from mutations in the two genes that make type I collagen, a protein important to bones and skin. These mutations cause the body to make either too little or poor-quality type I collagen. 1

Causes of Osteogenesis imperfecta: medical news summaries: The following medical news items are relevant to causes of Osteogenesis imperfecta:

Related information for causes of Osteogenesis imperfecta: Further relevant information on causes of Osteogenesis imperfecta may be found in the risk factors for Osteogenesis imperfecta and underlying causes of Osteogenesis imperfecta.

Footnotes:
1. excerpt from Questions and Answers about Heritable Disorders of Connective Tissue: NIAMS

Last revision: June 5, 2003

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