Medical Dictionary: Mosaicism
Mosaicism: Having two sets of cells with different genes
Introduction: The idea of mosaicism is that some people have two (or more) sets of cells with slightly different DNA. This is actually quite common with minor DNA differences (e.g. everyone's T-cells have varying DNA), but mosaicism is only of clinical interest when one set of cells has a particular genetic disease or chromosome disease, but the other set of cells has normal DNA. See also germinal mosaicism.
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Mosaicism: Another name for Germinal mosaicism.
Mosaicism (condition): Very rare genetic disease type where people have two types of cells
Mosaicism (condition): Sometimes even an autosomal dominant disease can arise surprisingly when neither parent has the disease. This can be due to a mutation (see sporadic genetic disease), but need not be, and it can also be due to "germinal mosaicism". This is a condition where one parent's gamete cells have the genetic defect, whereas their normal cells do not. These conditions are very rare.
More information on medical condition: Germinal mosaicism:
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