Medical Dictionary: Jakob's disease
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Jakob's disease: Another name for Creutzfeldt-Jakob Disease.
Jakob's disease (condition): Very rare prion brain disease
Jakob's disease (condition): Creutzfeldt-Jakob Disease (CJD) is a rare 1-in-a-million disease that occurs spontaneously, with 10-15% inheritance, and unrelated to animal diseases. It usually leads to dementia.
CJD is a rare brain disease in humans caused by abnormal brain proteins (prions). It is similar to the various transmissible spongiform encephalopathies that afflict animals including "mad cow disease". Unfortunately, prognosis for CJD is poor as there are no effective treatments against prions. CJD is not usually contagious, except rarely by direct exposure to the brain (such as brain surgery).
Because CJD is rare it is often misdiagnosed as other
Common misdiagnoses include
Alzheimer's disease, motor neurone disease, ALS,
Picks disease, Multi infarct Disease,
and metabolic encephalopathies.
Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably
fatal brain disorder.
It affects about one person in every one million
people per year worldwide; in the United States there are about 200 cases
CJD usually appears in later life and runs a rapid course.
Typically, onset of symptoms occurs about age 60, and about 90 percent of
patients die within 1 year. In the early stages of disease, patients may
have failing memory, behavioral changes, lack of coordination and visual
disturbances. As the illness progresses, mental deterioration becomes
pronounced and involuntary movements, blindness, weakness of extremities,
and coma may occur.
More information on medical condition: Creutzfeldt-Jakob Disease:
- Introduction: Creutzfeldt-Jakob Disease
- Basic Summary for Creutzfeldt-Jakob Disease
- Types of Creutzfeldt-Jakob Disease
- Risk Factors for Creutzfeldt-Jakob Disease
- Symptoms of Creutzfeldt-Jakob Disease
- Complications of Creutzfeldt-Jakob Disease
- Diagnostic Tests for Creutzfeldt-Jakob Disease
- Misdiagnosis of Creutzfeldt-Jakob Disease
- Treatments for Creutzfeldt-Jakob Disease
1. excerpt from Creutzfeldt-Jakob Disease Fact Sheet: NINDS
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