Basic Summary for Metachromatic Leukodystrophy


Main name of condition: Metachromatic Leukodystrophy
Other names or spellings: MLD

What is Metachromatic Leukodystrophy?
  Brief description of Metachromatic Leukodystrophy: Brain myelin genetic disorder with various subtypes.
  Parent types of Metachromatic Leukodystrophy: Leukodystrophy, Brain conditions, Genetic Disease
  Organs Affected by Metachromatic Leukodystrophy: brain, spinal cord
  Types of Metachromatic Leukodystrophy: Late infantile MLD, Juvenile MLD, Adult MLD
Who gets Metachromatic Leukodystrophy?
  Patient Profile for Metachromatic Leukodystrophy: onset at 6 months to 2 years for infantile form; 4-14 years for juvenile; after 16 for adult form.
How serious is Metachromatic Leukodystrophy?
  Prognosis of Metachromatic Leukodystrophy: Poor. Life-shortening. Often death 3-6 years after onset for infantile form; death within 6-14 years of onset for other forms.
  Prognosis of Metachromatic Leukodystrophy: The prognosis for MLD is poor. Death generally occurs within 6 to 14 years after onset of symptoms. In the infantile form death may occur between 3 and 6 years after onset. 1
What causes Metachromatic Leukodystrophy?
  Class of Condition for Metachromatic Leukodystrophy: genetic
What are the symptoms of Metachromatic Leukodystrophy?
  Symptoms of Metachromatic Leukodystrophy: see symptoms of Metachromatic Leukodystrophy
Can anyone else get Metachromatic Leukodystrophy?
  Contagion of genetic conditions: generally not; see details in contagion of genetic diseases.
  Inheritance of genetic conditions: see details in inheritance of genetic diseases.
How is it treated?
  Treatments for Metachromatic Leukodystrophy: see treatments for Metachromatic Leukodystrophy

1. excerpt from NINDS Metachromatic Leukodystrophy Information Page: NINDS

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