Introduction: Lymphocytic Choriomeningitis


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Lymphocytic Choriomeningitis: Rodent-borne viral disease often causing meningitis or encephalitis

Lymphocytic Choriomeningitis: Lymphocytic choriomeningitis, or LCM, is a rodent-borne viral infectious disease that presents as aseptic meningitis (inflammation of the membrane, or meninges, that surrounds the brain and spinal cord), encephalitis (inflammation of the brain), or meningoencephalitis (inflammation of both the brain and meninges). Its causative agent is the lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae, that was initially isolated in 1933. Although LCMV is most commonly recognized as causing neurological disease, as its name implies, asymptomatic infection or mild febrile illnesses are common clinical manifestations. Additionally, pregnancy-related infection has been associated with abortion, congenital hydrocephalus and chorioretinitis, and mental retardation. 1

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Footnotes:
1. excerpt from Lymphocytic Choriomeningitis: DVRD

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