Cure Research for Type 2 diabetes


Research discussion: The DCCT is a clinical study conducted from 1983 to 1993 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The study showed that keeping blood glucose levels as close to normal as possible slows the onset and progression of eye, kidney, and nerve diseases caused by diabetes. In fact, it demonstrated that any sustained lowering of blood glucose helps, even if the person has a history of poor control.

The largest, most comprehensive diabetes study ever conducted, the DCCT involved 1,441 volunteers with type 1 diabetes and 29 medical centers in the United States and Canada. Volunteers had diabetes for at least 1 year but no longer than 15 years. They also were required to have no, or only early signs of, diabetic eye disease.

The study compared the effects of two treatment regimens--standard therapy and intensive control--on the complications of diabetes. Volunteers were randomly assigned to each treatment group.1

Over the years, scientists have been trying to find noninvasive ways for people with diabetes to measure their blood glucose. Most methods of monitoring blood glucose require a blood sample, usually obtained by using an automatic lancing device on a finger. Some meters use a blood sample from a less sensitive area, such as the upper arm, forearm, or thigh. Some devices use a beam of light instead of a lancet to pierce the skin. 2

In recent years, advances in diabetes research have led to better ways to manage diabetes and treat its complications. For example, the insulin pump, new oral medications, and better ways of monitoring blood glucose have become available. In the future, it may be possible to administer insulin through inhalers, a pill, or a patch. Devices are also being developed that can monitor blood glucose levels without having to prick a finger to get a blood sample. Researchers continue to search for the cause or causes of diabetes and ways to prevent and cure the disorder. 3

Medical research for Type 2 diabetes: medical news summaries: The following medical news items are relevant to medical research for Type 2 diabetes:

1. excerpt from Diabetes Control and Complications Trial (DCCT): NIDDK
2. excerpt from Noninvasive Blood Glucose Monitors: NIDDK
3. excerpt from Diabetes: NWHIC

Last revision: April 10, 2003

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