Causes of Type 1 diabetes


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Cause of Type 1 diabetes: Autoimmune attack against the pancreas's insulin-producing cells.

Cause of Type 1 diabetes: Type 1 diabetes is an autoimmune disease. An autoimmune disease results when the body's system for fighting infection (the immune system) turns against a part of the body. In diabetes, the immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin. Someone with type 1 diabetes needs to take insulin daily to live. 1

Triggers list for Type 1 diabetes: The list of triggers mentioned in source as possible causal factors for Type 1 diabetes includes:

  • Viruses - although unclear, various viruses have been mentioned as potential triggers.
  • Cow milk protein - certain unconfirmed theories exist about molecular mimicry between cow milk and pancreas islet cells.

Cause details for Type 1 diabetes: Type 1 diabetes mellitus results from autoimmune destruction of the insulin-producing cells of the pancreas. Insulin is required by the body to keep the blood sugar (glucose) level under control. High levels of glucose are responsible for the symptoms and the complications of the disease. However, most of the insulin-producing cells are destroyed before the patient develops symptoms of diabetes2

An autoimmune disease results when the body's system for fighting infection (the immune system) turns against a part of the body. In type 1 diabetes, the immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin, thereby preventing cells from taking up sugar from blood.3

Underlying condition causes of Type 1 diabetes: The list of possible underlying conditions (see also Misdiagnosis of underlying causes of Type 1 diabetes) mentioned in various sources as possible causes of Type 1 diabetes includes:

Type 1 diabetes as a complication: Other conditions that might have Type 1 diabetes as a complication might be potential underlying causes of Type 1 diabetes. The list of conditions listing Type 1 diabetes as a complication in our database includes:

Causes of Type 1 diabetes: medical news summaries: The following medical news items are relevant to causes of Type 1 diabetes:

Related information for causes of Type 1 diabetes: Further relevant information on causes of Type 1 diabetes may be found in the risk factors for Type 1 diabetes and underlying causes of Type 1 diabetes.

Footnotes:
1. excerpt from Diabetes Overview: NIDDK
2. excerpt from Understanding Autoimmune Disease: NIAID
3. excerpt from Diabetes: NWHIC

Last revision: April 10, 2003

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