Cure Research for Depression


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Research list: The list of research areas and treatments under analysis mentioned in various sources for Depression includes:

Research discussion: NIMH has initiated a large-scale, controlled clinical trial at 10 sites across the U.S. to compare the long-term effectiveness of fluoxetine, CBT, and the combination of these interventions for treatment of depression in adolescents. More information about this trial, called the Treatment of Adolescents with Depression Study (TADS), and others can be found through the Clinical Trials page of the NIMH web site at http://www.nimh.nih.gov/studies/index.cfm. 1

Because of the widespread interest in St. John's wort, the National Institutes of Health (NIH) is conducting a 3-year study, sponsored by three NIH components-the National Institute of Mental Health, the National Center for Complementary and Alternative Medicine, and the Office of Dietary Supplements. The study is designed to include 336 patients with major depression, randomly assigned to an 8-week trial with one-third of patients receiving a uniform dose of St. John's wort, another third a selective serotonin reuptake inhibitor commonly prescribed for depression, and the final third a placebo (a pill that looks exactly like the SSRI and the St. John's wort, but has no active ingredients). The study participants who respond positively will be followed for an additional 18 weeks. After the 3-year study has been completed, results will be analyzed and published. 2

Medical research for Depression: medical news summaries: The following medical news items are relevant to medical research for Depression:



Footnotes:
1. excerpt from Depression in Children and Adolescents A Fact Sheet for Physicians: NIMH
2. excerpt from Depression: NIMH

Last revision: July 1, 2003

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