Introduction: Creutzfeldt-Jakob Disease


Creutzfeldt-Jakob Disease: Creutzfeldt-Jakob Disease (CJD) is a rare 1-in-a-million disease that occurs spontaneously, with 10-15% inheritance, and unrelated to animal diseases. It usually leads to dementia.

CJD is a rare brain disease in humans caused by abnormal brain proteins (prions). It is similar to the various transmissible spongiform encephalopathies that afflict animals including "mad cow disease". Unfortunately, prognosis for CJD is poor as there are no effective treatments against prions. CJD is not usually contagious, except rarely by direct exposure to the brain (such as brain surgery).

Because CJD is rare it is often misdiagnosed as other brain-related diseases. Common misdiagnoses include Alzheimer's disease, motor neurone disease, ALS, Picks disease, Multi infarct Disease, and metabolic encephalopathies.

Creutzfeldt-Jakob Disease: Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. It affects about one person in every one million people per year worldwide; in the United States there are about 200 cases per year. CJD usually appears in later life and runs a rapid course. Typically, onset of symptoms occurs about age 60, and about 90 percent of patients die within 1 year. In the early stages of disease, patients may have failing memory, behavioral changes, lack of coordination and visual disturbances. As the illness progresses, mental deterioration becomes pronounced and involuntary movements, blindness, weakness of extremities, and coma may occur. 1

Researching symptoms of Creutzfeldt-Jakob Disease: Further information about the symptoms of Creutzfeldt-Jakob Disease is available including a list of symptoms of Creutzfeldt-Jakob Disease, other diseases that might have similar symptoms in differential diagnosis of Creutzfeldt-Jakob Disease, or alternatively return to research other symptoms in the symptom center.

Misdiagnosis and Creutzfeldt-Jakob Disease: Research more detailed information about misdiagnosis of Creutzfeldt-Jakob Disease, underlying causes of Creutzfeldt-Jakob Disease (possibly misdiagnosed), or research misdiagnosis of other diseases

Treatments for Creutzfeldt-Jakob Disease: Various information is available about treatments available for Creutzfeldt-Jakob Disease, current research about Creutzfeldt-Jakob Disease treatments, or research treatments for other diseases.

Causes of Creutzfeldt-Jakob Disease: Research more detailed information about the causes of Creutzfeldt-Jakob Disease, other possibly hidden causes of Creutzfeldt-Jakob Disease, or other general information about Creutzfeldt-Jakob Disease.

Statistics and Creutzfeldt-Jakob Disease: Various sources and calculations are available in statistics about Creutzfeldt-Jakob Disease, prevalence and incidence statistics for Creutzfeldt-Jakob Disease, and you can also research other medical statistics in our statistics center.

         Contents for Creutzfeldt-Jakob Disease:

1. excerpt from Creutzfeldt-Jakob Disease Fact Sheet: NINDS

Last revision: May 26, 2003

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