Basic Summary for Creutzfeldt-Jakob Disease


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Main name of condition: Creutzfeldt-Jakob Disease
Other names or spellings: CJD, Jakob's disease, Jakob-Creutzfeldt disease


What is Creutzfeldt-Jakob Disease?
  Brief description of Creutzfeldt-Jakob Disease: Very rare prion brain disease
  Parent types of Creutzfeldt-Jakob Disease: Prion diseases, Transmissible Spongiform Encephalopathy, Brain conditions
  Organs Affected by Creutzfeldt-Jakob Disease: brain
  Types of Creutzfeldt-Jakob Disease: Sporadic CJD, Hereditary CJD, Variant CJD, Acquired CJD
How many people get Creutzfeldt-Jakob Disease?
  Incidence (annual) of Creutzfeldt-Jakob Disease: 1-per-million
  Incidence Rate of Creutzfeldt-Jakob Disease: approx 1 in 1,000,000 or 0.00% or 271 people in USA [about data]
  Prevalance of Creutzfeldt-Jakob Disease: It affects about one person in every one million people per year worldwide; in the United States there are about 200 cases per year. 1 ... On the basis of mortality surveillance from 1979 to 1994, the annual incidence of CJD remained stable at approximately 1 case per million persons in the United States. 2 ... The usual type of CJD occurs worldwide and strikes about one in a million people per year.3
Who gets Creutzfeldt-Jakob Disease?
  Profile for Creutzfeldt-Jakob Disease: Typically, onset of symptoms occurs at about age 60. 4 ... The disease is found most frequently in patients 55-65 years of age, but cases can occur in persons older than 90 years and younger than 55 years of age. 2 ... Most people with CJD are between 55 and 79 years old.3
How serious is Creutzfeldt-Jakob Disease?
  Prognosis of Creutzfeldt-Jakob Disease: Poor. Typically death within 12 months.
  Prognosis of Creutzfeldt-Jakob Disease: About 90 percent of patients die within 1 year. In the early stages of disease, patients may have failing memory, behavioral changes, lack of coordination and visual disturbances. As the illness progresses, mental deterioration becomes pronounced and involuntary movements, blindness, weakness of extremities, and coma may occur. 4
  Complications of Creutzfeldt-Jakob Disease: see complications of Creutzfeldt-Jakob Disease
What causes Creutzfeldt-Jakob Disease?
  Class of Condition for Creutzfeldt-Jakob Disease: prion
  Causes of Creutzfeldt-Jakob Disease: see causes of Creutzfeldt-Jakob Disease
  Risk factors for Creutzfeldt-Jakob Disease: see risk factors for Creutzfeldt-Jakob Disease
What are the symptoms of Creutzfeldt-Jakob Disease?
  Duration of Creutzfeldt-Jakob Disease: In more than 85 percent of cases, the duration of CJD is less than 1 year (median: 4 months) after onset of symptoms. 2
  Symptoms of Creutzfeldt-Jakob Disease: see symptoms of Creutzfeldt-Jakob Disease
Can anyone else get Creutzfeldt-Jakob Disease?
  Contagion of Creutzfeldt-Jakob Disease: Not generally contagious. Not even by blood transfusion. Very rarely by direct brain contagion such as in brain surgery or organ transplants; see contagion of prion diseases.
  More information: see contagiousness of Creutzfeldt-Jakob Disease
  Inheritance: see inheritance of Creutzfeldt-Jakob Disease
How is it treated?
  Treatments for Creutzfeldt-Jakob Disease: see treatments for Creutzfeldt-Jakob Disease
  Research for Creutzfeldt-Jakob Disease: see research for Creutzfeldt-Jakob Disease

Footnotes:
1. excerpt from Creutzfeldt-Jakob Disease Fact Sheet: NINDS
2. excerpt from Facts About Creutzfeldt-Jakob Disease: CDC-OC
3. excerpt from Update Follow-Up Study of NHPP Growth Hormone Recipients: NIDDK
4. excerpt from NINDS Creutzfeldt-Jakob Disease Information Page: NINDS

Last revision: May 26, 2003

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