Diagnostic Tests for Celiac Disease
Diagnostic Test list for Celiac Disease: The list of diagnostic tests mentioned in various sources as used in the diagnosis of Celiac Disease includes:
- Gluten antibodies
- Antigliadin antibody test
- Anti-endomysium antibody test
- Antireticulin antibody test
- Small intestine biopsy
- Recovery from gluten-free diet - A positive recovery after a change to a gluten-free diet may help confirm celiac. However, since this diet is such a major change, and removes numerous types of food from the diet, it is still possible that the correct diagnosis is not celiac, but some other dietary intolerance.
Tests and diagnosis discussion for Celiac Disease: Diagnosing celiac disease can be difficult because some of its symptoms are similar to those of other diseases, including irritable bowel syndrome, Crohn's disease, ulcerative colitis, diverticulosis, intestinal infections, chronic fatigue syndrome, and depression.
Recently, researchers discovered that people with celiac disease have higher than normal levels of certain antibodies in their blood. Antibodies are produced by the immune system in response to substances that the body perceives to be threatening. To diagnose celiac disease, physicians test blood to measure levels of antibodies to gluten. These antibodies are antigliadin, anti-endomysium, and antireticulin.
If the tests and symptoms suggest celiac disease, the physician may remove a tiny piece of tissue from the small intestine to check for damage to the villi. This is done in a procedure called a biopsy: the physician eases a long, thin tube called an endoscope through the mouth and stomach into the small intestine, and then takes a sample of tissue using instruments passed through the endoscope. Biopsy of the small intestine is the best way to diagnose celiac disease.
Screening for celiac disease involves testing asymptomatic people for the antibodies to gluten. Americans are not routinely screened for celiac disease. However, because celiac disease is hereditary, family members--particularly first-degree relatives--of people who have been diagnosed may need to be tested for the disease. About 10 percent of an affected person's first-degree relatives (parents, siblings, or children) will also have the disease. The longer a person goes undiagnosed and untreated, the greater the chance of developing malnutrition and other complications. 1
Diagnosis of Celiac Disease: medical news summaries: The following medical news items are relevant to diagnosis of Celiac Disease:
1. excerpt from Celiac Disease: NIDDK
Last revision: April 9, 2003
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