Ménétrier's Disease: NIDDK
Article title: Ménétrier's Disease: NIDDK
Main condition: Menetrier's disease
Conditions: Menetrier's disease
Ménétrier's disease causes giant folds of tissue to grow in the wall of the stomach. The tissue may be inflamed and may contain ulcers. The disease also causes glands in the stomach to waste away and interferes with the body's absorption of a protein called albumin. Ménétrier's disease increases a person's risk of stomach cancer. People who have this rare, chronic disease are usually men between ages 30 and 60. The cause of the disease is unknown.
Symptoms include pain or discomfort and tenderness in the top middle part of the abdomen, loss of appetite, nausea, vomiting, diarrhea, vomiting blood, swelling in the abdomen, and ulcer-like pain after eating.
Ménétrier's disease is diagnosed through x-rays, endoscopy, and biopsy of stomach tissue. Endoscopy involves looking at the inside of the stomach using a long, lighted tube that is inserted through the mouth. Biopsy involves removing a tiny piece of stomach tissue to examine under the microscope for signs of disease.
Treatment may include medications to relieve ulcer symptoms and treat inflammation, and a high-protein diet. Part or all of the stomach may need to be removed if the disease is severe.
More information is available from
Additional Information on Ménétrier's Disease
The National Digestive Diseases Information Clearinghouse collects resource information on digestive diseases for the Combined Health Information Database (CHID). CHID is a database produced by health-related agencies of the Federal Government. This database provides titles, abstracts, and availability information for health information and health education resources.
To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of CHID. To obtain this information you may view the results of the automatic search on Ménétrier's Disease.
Or, if you wish to perform your own search of the database, you may access the CHID Online web site and search CHID yourself.
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E-mail: National Digestive Diseases Information Clearinghouse
The National Digestive Diseases Information Clearinghouse (NDDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). NIDDK is part of the National Institutes of Health under the U.S. Department of Health and Human Services. Established in 1980, the clearinghouse provides information about digestive diseases to people with digestive disorders and to their families, health care professionals, and the public. NDDIC answers inquiries; develops, reviews, and distributes publications; and works closely with professional and patient organizations and Government agencies to coordinate resources about digestive diseases.
Publications produced by the clearinghouse are carefully reviewed for scientific accuracy, content, and readability.
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NIH Publication No. 99-4639
e-text last updated: February 2000
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