Symptoms of Autoimmune Lymphoproliferative Syndrome


General information about symptoms of Autoimmune Lymphoproliferative Syndrome: The symptom information on this page attempts to provide a list of some possible symptoms of Autoimmune Lymphoproliferative Syndrome. This symptom information has been gathered from various sources, may not be fully accurate, and may not be the full list of symptoms of Autoimmune Lymphoproliferative Syndrome. Furthermore, symptoms of Autoimmune Lymphoproliferative Syndrome may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of symptoms and whether they are indeed symptoms of Autoimmune Lymphoproliferative Syndrome.

List of symptoms of Autoimmune Lymphoproliferative Syndrome: The list of symptoms mentioned in various sources for Autoimmune Lymphoproliferative Syndrome includes:

Symptoms of Autoimmune Lymphoproliferative Syndrome: Some signs of ALPS are ones that people can feel or see, and some of them can be detected only by laboratory tests. Not all people with ALPS will have all of its possible symptoms. Some people have only a few. Some things that are seen most often in people with ALPS include:

  • an enlarged spleen
  • enlarged lymph nodes, especially in the neck and underarms
  • an enlarged liver
  • skin rashes
  • frequent nose bleeds
  • anemia (low blood counts)
  • an increase in certain types of white blood cells (including double-negative T cells)
  • an increased life-span of some white blood cells that are no longer needed
  • an alteration in a gene

Common autoimmune problems in ALPS include:

  • Very low red blood cell counts (hemolytic anemia) that can make one weak.
  • Very low platelet counts (immune-mediated thrombocytopenia, or ITP) that cause bruises and nose bleeds, and may pose a risk for hemorrhage (excessive bleeding). Little spots called petechiae (pet-eek'-ia) may also show up on the skin when platelets are low.
  • Very low white blood cell counts (autoimmune neutropenia), creating a risk for bacterial infection.
  • Less often, other autoimmune problems can occur in almost any organ - skin, liver, kidney and nerves are examples.

More symptoms of Autoimmune Lymphoproliferative Syndrome: In addition to the above information, to get a full picture of the possible symptoms of this condition and its related conditions, it may be necessary to examine symptoms that may be caused by complications of Autoimmune Lymphoproliferative Syndrome, underlying causes of Autoimmune Lymphoproliferative Syndrome, associated conditions for Autoimmune Lymphoproliferative Syndrome, risk factors for Autoimmune Lymphoproliferative Syndrome, or other related conditions.

Medical articles on symptoms: These general reference articles may be of interest:

1. excerpt from Autoimmune Lymphoproliferative Syndrome (ALPS): NIAID

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